Telford Hospital Participates in New Covid Vaccine Study for Pregnant Women
After 130,000 pregnant women vaccinated in the United States and no safety concerns were raised, the Pfizer and Moderna vaccines were recommended by the independent experts of the Joint Committee on Vaccination and Immunization of Pregnant Women in the United Kingdom .
Almost 52,000 pregnant women in England have now been vaccinated – likewise, with no safety concerns reported.
Data released last week by NHS England and the University of Oxford also shows that no pregnant woman who received both doses of a vaccine has been admitted to hospital with Covid-19.
Only three were admitted after receiving their first dose, meaning that 98% of those admitted to hospital did not receive a vaccine.
The Preg-CoV study, supported by £ 7.5million in government funding and led by St George’s, University of London, will provide vital clinical trial data on the immune response to vaccination at different dose intervals – either four to six weeks or eight to 12 weeks.
This data will help determine the best dosage interval and understand how the vaccine works to protect pregnant women and their babies against Covid-19.
Covid-19 Vaccine Deployment Minister Nadhim Zahawi said: “Pregnant women are more likely to fall seriously ill from Covid-19 and we know vaccines are safe for them and make a huge difference – in fact, no pregnant woman with two injections required hospitalization with Covid-19.
“This government-backed trial will provide more data on how best to protect pregnant women and their babies, and we can use this evidence to inform future immunization programs.
“I encourage anyone who is pregnant and eligible to register and contribute to research that will save lives for years to come.”
The trial will involve more than 600 pregnant women vaccinated with the Pfizer or Moderna vaccine.
They will be closely monitored by health professionals throughout their pregnancy and after childbirth.
Participants must be between 18 and 44 years old, have no health problems and be pregnant between 13 and 34 weeks on the day of the vaccination.
They will receive two doses of a vaccine – or one dose if they have already had their first – either at the shorter interval of four to six weeks or at the longer interval of eight to 12 weeks.
They will need to attend nine visits in total and will be required to complete an electronic diary between visits on all symptoms.
They will also receive a 24-hour cell phone number so they can contact one of the trial team members at any time if they have any concerns.
Scientists behind the trial will analyze blood samples from participants and a blood sample from their newborns, as well as breast milk samples.
They will use the samples to better understand how vaccines protect these people from Covid-19, with the first results expected by the end of the year.
The study is open to volunteer applications, with vaccinations starting in mid-August.
The trial will be conducted at 13 National Institute for Health Research sites in England, including Princess Royal Hospital in Telford.